Original Research

Health-related quality of life and demographic profiling of patients with selected noncommunicable diseases

Lynn Smith, Heather Morris-Eyton
Health SA Gesondheid | Vol 31 | a3379 | DOI: https://doi.org/10.4102/hsag.v31i0.3379 | © 2026 Lynn Smith, Heather Morris-Eyton | This work is licensed under CC Attribution 4.0
Submitted: 11 December 2025 | Published: 19 June 2026

About the author(s)

Lynn Smith, Department of Sport and Movement Studies, Faculty of Health Sciences, University of Johannesburg, Johannesburg, South Africa
Heather Morris-Eyton, Department of Sport and Movement Studies, Faculty of Health Sciences, University of Johannesburg, Johannesburg, South Africa

Abstract

Background: Health-related quality of life (HRQoL) reflects physical, mental and socioeconomic well-being. In people living with chronic noncommunicable diseases (NCDs), HRQoL is an important indicator of treatment effectiveness and long-term outcomes. Understanding domain-specific strengths and vulnerabilities can support person-centred care.
Aim: To determine the demographic profile and HRQoL of adults living with hypertension, type 2 diabetes mellitus and/or cardiovascular disease (CVD).
Setting: Public and private healthcare facilities in the Johannesburg metropolitan district, South Africa.
Methods: A quantitative cross-sectional survey was conducted. Using purposive stratified random sampling, 257 adults with hypertension, type 2 diabetes mellitus and/or CVD completed the 37-item Smith Toolkit for Integrated Health-Related Quality of Life. The instrument assesses physical, mental and socioeconomic domains and demonstrated strong reliability. Data were collected in person and online and analysed descriptively using SPSS version 28.
Results: Overall HRQoL was moderate to high (77.70 ± 12.91). Physical health scores were strong (80.31 ± 15.78), with favourable ratings for symptoms, work functioning and physical limitations, although vitality was lower (52.40 ± 34.01). Mental health scores were moderate (72.02 ± 17.19), with lower self-efficacy and evidence of psychological challenges. Socioeconomic health was strong (81.49 ± 17.66), supported by high perceived social support, financial stability and relationship quality.
Conclusion: Participants generally reported good HRQoL despite living with chronic NCDs. However, lower vitality and self-efficacy indicate important gaps in psychological and behavioural functioning. Interventions targeting fatigue, resilience and self-management may further improve well-being and health outcomes.
Contribution: This study provides context-specific evidence on HRQoL among South Africans living with NCDs and highlights the value of holistic, interdisciplinary and person-centred care.


Keywords

noncommunicable diseases; health-related quality of life; patient-reported outcomes; chronic disease; multimorbidity

Sustainable Development Goal

Goal 3: Good health and well-being

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