Original Research

A cross-sectional study on the long-term impact of COVID-19: Symptoms, disability and daily functioning

Soraya Maart, Rebecca A. Hofmeyr, Justin J. Muller, Lehlohonlo B. Tserere
Health SA Gesondheid | Vol 30 | a2880 | DOI: https://doi.org/10.4102/hsag.v30i0.2880 | © 2025 Soraya Maart, Rebecca A. Hofmeyr, Justin J. Muller, Lehlohonlo B. Tserere | This work is licensed under CC Attribution 4.0
Submitted: 30 September 2024 | Published: 09 July 2025

About the author(s)

Soraya Maart, Department of Health and Rehabilitation Sciences, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
Rebecca A. Hofmeyr, Department of Health and Rehabilitation Sciences, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
Justin J. Muller, Department of Health and Rehabilitation Sciences, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
Lehlohonlo B. Tserere, Department of Health and Rehabilitation Sciences, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa

Abstract

Background: Evidence suggests that survivors of coronavirus disease 2019 (COVID-19) experience ongoing symptoms, which is known as long COVID, or post-COVID syndrome. Approximately 100 million people globally are experiencing long COVID symptoms. Post-COVID syndrome (PCS) has debilitating effects on functioning and quality of life, potentially qualifying it as a disability.

Aim: This study aimed to assess the impact of PCS on disability levels using the WHO Disability Assessment Schedule (WHODAS 2.0).

Setting: A digital cross-sectional survey was conducted through online platforms, including Facebook, WhatsApp, and Instagram.

Methods: A self-developed questionnaire was distributed via social media to collect demographic information, COVID-19 symptoms, and severity. The WHODAS 2.0 instrument was used to measure disability levels. A total of 101 participants completed the online survey.

Results: Most participants were aged between 21 years and 30 years (66%) and were female (60%). The most common acute COVID-19 symptoms were sore throat, fever, and headaches (84%). Post-COVID symptoms included brain fog and tiredness (82%). There was a statistically significant relationship between brain fog, depression, anxiety, and disability summary scores (p < 0.005). The mean WHODAS 2.0 score was 34%, indicating a moderate level of disability.

Conclusion: This study’s results align with previous research, highlighting tiredness and neuropsychiatric symptoms as common among post-COVID patients. Post-COVID syndrome results in moderate disability when assessed using the WHODAS 2.0 with domains of Life Activities and Cognition mostly affected.

Contribution: Post-COVID syndrome should be recognised as a disabling health condition, with rehabilitation prioritised as a critical intervention to enhance functional capacity and quality of life.


Keywords

COVID-19; post-COVID syndrome; disability; WHODAS 2.0; long COVID functioning.

Sustainable Development Goal

Goal 3: Good health and well-being

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